Artículos Científicos

Martín F, Blanco M, Zambrano P, Cáceres O, Almirall M, Alegre-Martín J, Lobo B, González-Castro Ana M, Santos J, Domingo JC, Jurek J, Castro-Marrero J. Increased gut permeability and bacterial translocation are associated with fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome: implications for disease-related biomarker discovery. Front. Immunol., 07 September 2023 Sec. Mucosal Immunity. Volume 14 – 2023
Pareja JL, Cáceres O, Zambrano P, Martín F, Berral FJ, Blanco M. Treatment with low-intensity transcranial magnetic stimulation in women with fibromyalgia improves diagnostic variables up to 6 months after treatment completion. Clin Exp Rheumatol. 2022 Jun;40(6):1112-1118. doi: 10.55563/clinexprheumatol/gd4v6h. Epub 2021 Nov 29. PMID: 34905482.
Blanco Suárez, M., Zambrano Chacón, P., Cáceres Calle, Ó., Dios Beas Jiménez, J. D., Martín Bermudo, F. M., & Berral de la Rosa, F. (2019). Overtraining Syndrome: one more piece of the Central Sensitivity Syndrome puzzle. Rev. andal. med. deporte, 131-134.
Rivera, J., Rodríguez, T., Pallarés, M., Castrejón, I., González, T., Vallejo-Slocker, L., … & Collado, A. (2022). Prevalence of post-COVID-19 in patients with fibromyalgia: a comparative study with other inflammatory and autoimmune rheumatic diseases. BMC Musculoskeletal Disorders, 23(1), 471.
Archie, S. R., Al Shoyaib, A., & Cucullo, L. (2021). Blood-brain barrier dysfunction in CNS disorders and putative therapeutic targets: an overview. Pharmaceutics, 13(11), 1779.
Natalia Núñez Pérez, Paola Z Chacón, Oscar Cáceres Calle, Manuel Blanco Suárez. Valoración de la estimulación transcraneal por corriente directa (tDCS) anódica en pacientes afectados de migraña en el entorno del Síndrome de Sensibilidad Central. Poster presentado en II Simposio internacional de Síndrome de Sensibilidad Central 2018.
Francisco Martín Bermudo, Manuel Blanco Suárez, Oscar Cáceres Calle, Paola Z Chacón. Permeabilidad intestinal una pieza más del puzzle del Síndrome de Sensibilidad Central. Presentado en II Simposio internacional de Síndrome de Sensibilidad Central 2018.
Manuel Blanco Suárez, Oscar Cáceres Calle, Francisco Martín Bermudo, Paola Z Chacón. Impacto de la estimulación mágnetica transcraneal de bajo campo en pacientes diagnosticados de fibromialgia. Presentado en II Simposio internacional de Síndrome de Sensibilidad Central 2018.
Oscar Cáceres Calle, Manuel Blanco Suárez, Francisco Martín Bermudo, Paola Z Chacón, María Rodríguez Quirós, Marta Fernández de Angulo. Influencia de dietas terapéuticas exentas de leche y trigo en pacientes con Síndrome de Sensibilidad Central. Presentado en II Simposio internacional de Síndrome de Sensibilidad Central 2018
Paola Z Chacón, Óscar Cáceres Calle, Manuel Blanco Suárez. Tratamiento de oxigenoterapia de hipoxia de hiperoxia en pacientes con síndrome de fatiga crónica. Presentado en II Simposio internacional de Sindrome de Sensibilidad Central 2018.
Caro, X. J., & Winter, E. F. (2022). Unexpectedly high prevalence of primary immune deficiency in fibromyalgia: serologic features and clinical correlates. Clinical and Experimental Rheumatology, 40(6), 1076-1083.
Genuis, S. J. (2010). Sensitivity-related illness: the escalating pandemic of allergy, food intolerance and chemical sensitivity. Science of the Total Environment, 408(24), 6047-6061.
Barnes, J. G. (2001). ‘Sensitivity syndromes’ related to radiation exposures. Medical hypotheses, 57(4), 453-458.
Ursini, F., Ciaffi, J., Mancarella, L., Lisi, L., Brusi, V., Cavallari, C., … & Meliconi, R. (2021). Fibromyalgia: a new facet of the post-COVID-19 syndrome spectrum? Results from a web-based survey. RMD Open 7: e001735.
Li, H., Zhang, X., Xiang, C., Feng, C., Fan, C., Liu, M., … & Tang, W. (2021). Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation. Journal of Advanced Research, 33, 241-251.
De Luca, C., Scordo, M. G., Cesareo, E., Pastore, S., Mariani, S., Maiani, G.,& Raskovic, D. (2010).Biological definition of multiple chemical sensitivity from redox state and cytokine profiling and not from polymorphisms of xenobiotic-metabolizing enzymes. Toxicology and applied pharmacology,248(3), 285-292.
Staud, R. (2015). Cytokine and immune system abnormalities in fibromyalgia and other central sensitivity syndromes. Current rheumatology reviews, 11(2), 109-115.
S Boomershine, C. (2015). Fibromyalgia: the prototypical central sensitivity syndrome. Current rheumatology reviews, 11(2), 131-145.
Latremoliere, A., & Woolf, C. J. (2009). Central sensitization: a generator of pain hypersensitivity by central neural plasticity.The Journal of Pain, 10(9), 895-926.
Woolf, C. J. (1983). Evidence for a central component of post-injury pain hypersensitivity. Nature.
Woolf, C. J., & Ma, Q. (2007). Nociceptors—noxious stimulus detectors. Neuron, 55(3), 353-364.
Chen, X., Tanner, K., & Levine, J. D. (1999). Mechanical sensitization of cutaneous C-fiber nociceptors by prostaglandin E 2 in the rat. Neuroscience letters, 267(2), 105-108.
Guenther, S., Reeh, P. W., & Kress, M. (1999). Rises in [Ca2+] i mediate capsaicin‐and proton‐induced heat sensitization of rat primary nociceptive neurons. European Journal of Neuroscience, 11(9), 3143-3150.
Hucho, T., & Levine, J. D. (2007). Signaling pathways in sensitization: toward a nociceptor cell biology. Neuron, 55(3), 365-376.
Pethö, G., Derow, A., & Reeh, P. W. (2001). Bradykinin‐induced nociceptor sensitization to heat is mediated by cyclooxygenase products in isolated rat skin. European Journal of Neuroscience, 14(2), 210-218.
Pezet, S., Marchand, F., D’Mello, R., Grist, J., Clark, A. K., Malcangio, M. & McMahon, S. B. (2008). Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions. The Journal of Neuroscience, 28(16), 4261-4270.
Tao, Y. X., Huang, Y. Z., Mei, L., & Johns, R. A. (2000). Expression of PSD-95/SAP90 is critical for N-methyl-D-aspartate receptor-mediated thermal hyperalgesia in the spinal cord. Neuroscience, 98(2), 201-206.
Liu, X. J., Gingrich, J. R., Vargas-Caballero, M., Dong, Y. N., Sengar, A., Beggs, S. & Salter, M. W. (2008). Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex. Nature medicine, 14(12), 1325-1332.
Lin Q, Palecek J, Paleckova V, Peng YB, Wu J, Cui M, Willis WD. Nitric oxide mediates the central sensitization of primate spinothalamic tract neurons. J Neurophysiol 1999;81:1075–108
Lin, Q. I. N. G., Peng, Y. B., & Willis, W. D. (1996). Inhibition of primate spinothalamic tract neurons by spinal glycine and GABA is reduced during central sensitization. Journal of neurophysiology, 76(2), 1005-1014.
Governo, R. J. M., Morris, P. G., Prior, M. J. W., Marsden, C. A., & Chapman, V. (2006). Capsaicin-evoked brain activation and central sensitization in anaesthetised rats: a functional magnetic resonance imaging study. Pain,126(1), 35-45.
Sun RQ, Tu YJ, Lawand NB, Yan JY, Lin Q, Willis WD. Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization. J Neurophysiol 2004;92:2859–2866
Yunus, M. B. (2007). Role of central sensitization in symptoms beyond muscle pain, and the evaluation of a patient with widespread pain. Best Practice & Research Clinical Rheumatology, 21(3), 481-497.
Ren, K., & Torres, R. (2009). Role of interleukin-1β during pain and inflammation. Brain research reviews, 60(1), 57-64.
Desmeules, J. A., Cedraschi, C., Rapiti, E., Baumgartner, E., Finckh, A., Cohen, P. & Vischer, T. L. (2003). Neurophysiologic evidence for a central sensitization in patients with fibromyalgia. Arthritis & Rheumatism, 48(5), 1420-1429.
Katano, T., Furue, H., Okuda‐Ashitaka, E., Tagaya, M., Watanabe, M., Yoshimura, M., & Ito, S. (2008). N‐ethylmaleimide‐sensitive fusion protein (NSF) is involved in central sensitization in the spinal cord through GluR2 subunit composition switch after inflammation. European Journal of Neuroscience, 27(12), 3161-3170.
Yunus, M. B. (2008, June). Central sensitivity syndromes: a new paradigm and group nosology for fibromyalgia and overlapping conditions, and the related issue of disease versus illness. In Seminarsin arthritis and rheumatism (Vol. 37, No. 6, pp. 339-352). WB Saunders.
Kindler, L. L., Bennett, R. M., & Jones, K. D. (2011). Central sensitivity syndromes: mounting pathophysiologic evidence to link fibromyalgia with other common chronic pain disorders. Pain Management Nursing, 12(1), 15-24.
Lorduy, K. M., Liegey‐Dougall, A., Haggard, R., Sanders, C. N., & Gatchel, R. J. (2013). The prevalence of comorbid symptoms of central sensitization syndrome among three different groups of temporomandibular disorder patients. Pain Practice, 13(8), 604-613.